FDA Consumer

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According to a journal of the U.S. Food and Drug Administration called FDA Consumer “People who receive blood products, particularly plasma-containing products, may be at risk for developing transfusion-related acute lung injury (TRALI),” If this condition is not recognized and treated correctly, it may lead to death. “TRALI can occur when white blood cell antibodies in the donor’s blood react with the recipient’s white blood cells, causing a change in the lung tissue that allows fluid to enter. Most donors implicated in TRALI reactions are women with more than two children or donors who have had multiple transfusions.” Symptoms “include fever, shortness of breath, and a drop in blood pressure. X-rays often show the transfusion recipient’s lungs as completely white.”

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