Immune Serum Globulin

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Contents

An immumoglobulin or antibody is a protein mostly found in the blood plasma that is used by the immune system to identify and neutralize foreign objects like bacteria and viruses. Each antibody recognizes a specific antigen unique to its target.

Primary component of origin

Plasma.

Percent of component

Production

Pharmaceutical preparations of serum globulins are extracted from sequestered (separated) human or bovine blood.[1]

Medicinal Value

To provide immunity or help the body fight a disease process. The clinical use of immunoglobulins started in the 1950s, after the Second World War. These products were for intramuscular use and were indicated in the prevention of viral infections. Later this was extended to patients with severe immunodeficiencies. The introduction in the 1970s of immunoglobulins for intravenous use allowed their administration in higher doses.

Risks

Pharmaceuticals, found in

Anti-venoms, hepatitis, measles, rabies, tetanus and varicella vaccines, Rhogam (Anti-D).

Alternatives

Factoids

See also

Immune Globulin (Ig) Fact Sheet

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