Category:Oxygen Carriers
From Noblood
These solutions are being heralded as the first true blood substitutes, since when transfused into a patient they have the same function as the red blood cells.
- Hemoglobin Based (HBOCs)
- Perfluorocarbons
See also
Euro Blood Substitutes Oxycyte Oxycyte is the company’s perfluorocarbon (PFC) therapeutic oxygen carrier. It is designed to enhance oxygen delivery to damaged tissues. When used as an intravenous emulsion, Oxycyte can carry as much as five times more oxygen than hemoglobin, making it an effective means of transporting oxygen to tissues and carrying carbon dioxide to the lungs for disposal. Oxycyte is not a blood substitute. Because it is a PFC, and not based on hemoglobin, it does not have the safety issues associated with hemoglobin-based products. In fact, there have been no adverse events in company clinical trials that were related to Oxycyte. The chart below summarizes the advantages of Oxycyte.
PFC Advantages Hemoglobin
Superior safety profile
Reported safety issues
No supply issues
Outdated human blood/limited supply
No animal hemoglobin
Cow's blood
No disease transmission/typing, cross matching
Potential for disease transmission/antibody formation
The company believes Oxycyte has the potential for use in multiple indications, including traumatic brain injury, sickle-cell pain crisis, decompression sickness, stroke, heart attack, and wound treatment. The company estimates that the combined annual incidence for these indications in the United States and Europe is more than 12 million.
Pages in category "Oxygen Carriers"
The following 3 pages are in this category, out of 3 total.
